https://biomed.staff.au.dk/en-gbFri, 01 May 2026 08:28:16 +0200Fri, 01 May 2026 08:28:16 +0200TYPO3 EXT:newsnews-29554Tue, 05 May 2026 13:00:00 +0200https://phd.health.au.dk/display/artikel/phd-defence-camilla-groenkjaer-hoffHow lithium changes the kidney: Cellular Insights into Nephrogenic Diabetes InsipidusPhD defensePhD studentsPublic/MediaStaffHealthDepartment of BiomedicineGraduate School of HealthTue, 05 May 2026 13:00:00 +0200Tue, 05 May 2026 15:00:00 +0200Aarhus University, Jeppe Vontilius Auditorium (1252-310)Aarhus University, Jeppe Vontilius Auditorium (1252-310)1777978800177798600017779788001777986000news-29530Wed, 06 May 2026 12:00:00 +0200https://biomed.au.dk/display/artikel/biomedicine-seminar-25Lecturer Jean Farup: Fibro-adipogenic progenitors as directors of skeletal muscle repair and remodelingAbstract:
Skeletal muscle fibro-adipogenic progenitors (FAPs) have emerged as central regulators of skeletal muscle repair, orchestrating the balance between regeneration and degeneration. In this talk, I will present recent work showing how human FAP populations are functionally heterogeneous and highly responsive to the local muscle microenvironment. I will highlight evidence that specific FAP subsets promote fibrosis, fatty infiltration, and impaired regeneration in aging and metabolic disease, while others support productive tissue repair through interactions with muscle and immune cells. I will also discuss our recent findings on how FAPmacrophage communication contributes to muscle regeneration in elderly humans and how niche remodeling may shape repair outcomes. Together, these studies position FAPs not as passive bystanders, but as active directors of skeletal muscle remodeling, with important implications for understanding muscle loss and developing targeted therapies.

Bio:
Jean Farup is Associate Professor of Cellular Physiology at the Department of Biomedicine & Steno Diabetes Center Aarhus, where he leads a research group focused on skeletal muscle biology, regeneration, aging, and metabolic disease. His work centers on how the muscle microenvironment regulates tissue maintenance and repair, with particular emphasis on fibro-adipogenic progenitors and muscle stem cells. Farup has contributed important insights into muscle degeneration and impaired regeneration in aging and type 2 diabetes, using human muscle biopsies, primary cell isolation, flow cytometry, and spatial and single-cell omics.

]]>StaffDepartment of BiomedicineUlla Vosegaard AlsWed, 06 May 2026 12:00:00 +0200Wed, 06 May 2026 13:00:00 +0200Bldg. 1231-424 Lille Ana AudBldg. 1231-424 Lille Ana Aud1778061600177806520017780616001778065200news-29591Wed, 13 May 2026 13:00:00 +0200https://phd.health.au.dk/display/artikel/phd-defence-mads-christian-lamm-larsenNew research from Aarhus University sheds light on why patients with lupus develop blood clotsPhD defensePhD studentsPublic/MediaStaffHealthDepartment of BiomedicineGraduate School of HealthWed, 13 May 2026 13:00:00 +0200Wed, 13 May 2026 15:00:00 +0200Bartholin Auditorium, Building 1241-135, Aarhus University and onlineBartholin Auditorium, Building 1241-135, Aarhus University and online1778670000177867720017786700001778677200